Acta medica Hungarica
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Acta medica Hungarica · Jan 1989
Myasthenia gravis: familial occurrence. A study of 1100 myasthenia gravis patients.
Eleven-hundred myasthenia gravis cases observed by the author in a period of 37 years are reviewed. The ratio of familial incidence was 4.23%. Transitory (neonatal) myasthenia in new-born babies should be separated from the familial cases. ⋯ Some rare instances are reported, among them a unique family with six sisters suffering from myasthenia gravis. Genetic line and HLA antigens' role are dealt with. Observation of familial myasthenia cases may contribute to the knowledge of the immunologic and clinicopathologic background of the disease.
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Acta medica Hungarica · Jan 1989
Review Case ReportsTreatment of chronic pain syndromes with transcutaneous iontophoresis of vinca alkaloids, with special regard to post-herpetic neuralgia.
Successful treatment of 35 post-herpetic neuralgia (PHN) patients by means of transcutaneous iontophoresis of Vincristine is reported. This technique, based on transganglionic regulation--a novel neurobiological principle discovered by Csillik and Knyihár-Csillik-, alleviated pain in both fresh and inveterated PHN cases. Statistical analysis of the results excludes a placebo-like action.