Journal of psychoactive drugs
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J Psychoactive Drugs · Jul 2013
Randomized Controlled TrialPostoperative analgesia in the Jamaican cannabis user.
Anecdotal reports suggest that cannabis users require increased postoperative analgesia but there is insufficient supporting data. ⋯ Cannabis users require significantly more opioid rescue analgesia in the immediate postoperative period. Further research is needed to elucidate the precise mechanism by which this occurs.
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J Psychoactive Drugs · Jul 2013
The medicinal use of cannabis and cannabinoids--an international cross-sectional survey on administration forms.
Cannabinoids, including tetrahydrocannabinol and cannabidiol, are the most important active constituents of the cannabis plant. Over recent years, cannabinoid-based medicines (CBMs) have become increasingly available to patients in many countries, both as pharmaceutical products and as herbal cannabis (marijuana). While there seems to be a demand for multiple cannabinoid-based therapeutic products, specifically for symptomatic amelioration in chronic diseases, therapeutic effects of different CBMs have only been directly compared in a few clinical studies. ⋯ In general, herbal non-pharmaceutical CBMs received higher appreciation scores by participants than pharmaceutical products containing cannabinoids. However, the number of patients who reported experience with pharmaceutical products was low, limiting conclusions on preferences. Nevertheless, the reported data may be useful for further development of safe and effective medications based on cannabis and single cannabinoids.