Acta pharmacologica Sinica
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Acta Pharmacol. Sin. · Sep 2004
Anti-adjuvant arthritis of recombinant human endostatin in rats via inhibition of angiogenesis and proinflammatory factors.
To investigate the profile of endostatin on adjuvant arthritis (AA) and angiogenesis blockade in synovitis. ⋯ The recombinant human endostatin had an inhibitory effect on rat AA, which was related to its anti-angiogenesis and inhibition of proinflammatory cytokines.