Veterinary anaesthesia and analgesia
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Randomized Controlled Trial
High inspired oxygen concentrations increase intrapulmonary shunt in anaesthetized horses.
To compare pulmonary function and gas exchange in anaesthetized horses during and after breathing either O2-rich gas mixtures or air. ⋯ In healthy horses undergoing short-term dissociative anaesthesia, air breathing ensures a level of oxygen delivery that meets tissue demand. There is no benefit to horses in breathing O2-rich gas after the gas supply is discontinued. On the contrary, the degree of shunt induced by breathing O2-rich gas persists. The clinical relevance of this during recovery requires investigation.
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To determine the cardiopulmonary effects of desflurane (DES) in horses. ⋯ Desflurane concentrations between 1.0 and 1.75 x MAC(DES) reduces fr and VM but does not affect HR or MAP in horses.
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To examine the clinical suitability of medetomidine-propofol infusions for total intravenous anaesthesia in horses. ⋯ Medetomidine-propofol infusion produces adequate conditions for a range of surgical procedures. Cardiovascular function was adequate, as no pressor agents were required. Positive pressure ventilation was required in 23 horses.