Veterinary anaesthesia and analgesia
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To determine whether predictable alveolar concentrations of sevoflurane are reliably produced in dogs when liquid sevoflurane is injected into closed circuit breathing systems, as calculated by Lowe's square-root-of-time anaesthetic uptake model, and to confirm the validity of the model using soda lime and calcium hydroxide lime. ⋯ The model used in this study provided only an approximate guide to the volume of liquid sevoflurane required. Consequently, the definitive dose schedule must be based on measured anaesthetic concentrations and clinical monitoring.