Veterinary anaesthesia and analgesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparative study of three intramuscular anaesthetic combinations (medetomidine/ketamine, medetomidine/fentanyl/midazolam and xylazine/ketamine) in rabbits.
To compare the quality of surgical anaesthesia and cardiorespiratory effects of three intramuscular (IM) anaesthetic combinations in rabbits. ⋯ The quality of surgical anaesthesia was greatest with M-K. All combinations allowed recoveries of similar duration. It is theoretically possible to antagonize each component of the M-F-Mz combination.
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Randomized Controlled Trial Comparative Study Clinical Trial
Comparison between facemask and laryngeal mask airway in rabbits during isoflurane anesthesia.
To determine whether a laryngeal mask airway (LMA) provides a better airway than a facemask in spontaneously breathing anesthetized rabbits, and to test if it can be used for mechanically controlled ventilation. ⋯ The LMA can be used in rabbits but further work is needed before it is applied routinely.
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Evaluation of the LMA-ProSeal for positive pressure ventilation (PPV) in the pig. ⋯ Endotracheal intubation in pigs can be difficult so there is a risk of hypoxemia in the apnoeic animal. With the LMA-ProSeal the airway can be secured rapidly, safely and reliably. Use of the Standard-LMA under PPV can be associated with gas leakage into the stomach and the subsequent risk of gastric distension and regurgitation. Both the ability to drain the stomach and the high P(leak) of the LMA-ProSeal could contribute to improved protection against aspiration under PPV.
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Randomized Controlled Trial Clinical Trial
Effects of pre- versus post-anaesthetic buprenorphine on propofol-anaesthetized rats.
To compare the effect of pre- versus post-anaesthetic intramuscular (IM) buprenorphine on intermittent intravenous (IV) propofol anaesthesia in rats. ⋯ Buprenorphine administration at the start of periodic IV propofol anaesthesia in rats resulted in a significant reduction in the total propofol requirement and significantly improved the 1-hour post-anaesthesia recovery score. Clinical relevance Besides the ethical advantage of pre-emptive analgesia, pre-anaesthetic medication with buprenorphine in rats significantly reduces the total propofol requirements for surgical anaesthesia and in this study was found to be a safe and effective method of anaesthesia.