Veterinary anaesthesia and analgesia
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Randomized Controlled Trial
Changes in the minimum alveolar concentration of isoflurane and some cardiopulmonary measurements during three continuous infusion rates of dexmedetomidine in dogs.
To measure the change in the minimum alveolar concentration of isoflurane associated with three constant rate infusions of dexmedetomidine. ⋯ Dexmedetomidine infusions decrease the intra-operative requirement for isoflurane and may be useful in managing dogs undergoing surgery, where the provision of analgesia and limitation of the stress response is desirable.
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Randomized Controlled Trial
Cardiopulmonary effects of sufentanil long acting on sevoflurane anaesthesia in dogs.
To evaluate the cardiopulmonary effects of sufentanil long acting (SLA) in sevoflurane-anaesthetized dogs. ⋯ In spite of a moderate depressant effect on cardiorespiratory parameters, SLA may be of use as pre-anaesthetic medication before sevoflurane anaesthesia in dogs. Intermittent positive pressure ventilation may occasionally be necessary.
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Clinical Trial
The influence of butorphanol dose on characteristics of xylazine-butorphanol-propofol anesthesia in horses at altitude.
To characterize behavioral and physiological responses to short-term, unsupplemented intravenous (IV) anesthesia in healthy horses at high altitude (2240 m), and to test the hypothesis that the dose of butorphanol modifies the response of the horse to propofol anesthesia following xylazine pre-medication. ⋯ Dose of butorphanol did not markedly influence study results. Notably, low P(a)O(2) values related to geographic location of study and general anesthesia indicates a narrow margin of error for hypoxemia-related complications in anesthetized horses breathing unsupplemented air at high altitude.
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Comparative Study Clinical Trial
A comparison of extradural and intravenous methadone on intraoperative isoflurane and postoperative analgesia requirements in dogs.
To compare the effects of intravenous (IV) and extradural (ED) methadone on end-tidal isoflurane concentration (Fe'ISO) and postoperative analgesic requirements in dogs undergoing femoro-tibial joint surgery. ⋯ Extradural methadone provides safe and effective pain relief in dogs undergoing cruciate ligament repair.