Veterinary anaesthesia and analgesia
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To estimate the risk of death and identify the major risk factors for peri-anaesthetic mortality in great apes (Hominidae) that underwent anaesthesia in zoological collections in the UK and Ireland between 1 January 1990 and 30 June 2005. ⋯ This study has shown that great ape anaesthesia appears to carry a high risk of mortality. Sick and aged patients are at an increased risk of death and particular care should be exercised during their anaesthesia. Standardisation and completeness of anaesthetic records across zoological collections would assist greatly in further studies.
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To assess the changes in colloid osmotic pressure (COP) in horses undergoing surgery for colic. ⋯ Colloid osmotic pressure, like TP, decreased greatly over the course of crystalloid fluid infusion during anesthesia for laparotomy in horses with colic. This change may predispose the animal to tissue edema with subsequent morbidity.
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To measure concentrations of lidocaine serum after application of two 5% patches on horses. ⋯ Any analgesic effects that might be produced by application of 5% lidocaine patches on horses will not be due to systemic absorption of the drug.
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To evaluate the cardiovascular effects of norepinephrine (NE) and dobutamine (DB) in isoflurane-anesthetized foals. ⋯ Norepinephrine primarily augments arterial blood pressure while decreasing CI. Dobutamine primarily augments CI with only modest increases in arterial blood pressure. Both NE and DB could be useful in the hemodynamic management of anesthetized foals.
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Randomized Controlled Trial
Effect of intravenous lidocaine on heart rate, systolic arterial blood pressure and cough responses to endotracheal intubation in propofol-anaesthetized dogs.
To evaluate the effect of intravenous lidocaine on coughing and variations in heart rate (HR) and systolic arterial pressure (SAP) at endotracheal intubation in propofol-anaesthetized dogs. ⋯ Intravenous lidocaine had no effect on the occurrence or intensity of coughing or on changes in SAP at endotracheal intubation in dogs anaesthetized with propofol. The use of 1 mg kg(-1) lidocaine intravenously before intubation in dogs to attenuate cough and the pressor response was not supported.