The lancet oncology
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The lancet oncology · Dec 2011
Review Meta AnalysisPsychological morbidity and quality of life of ethnic minority patients with cancer: a systematic review and meta-analysis.
Ethnic minority is associated with higher cancer incidence and poorer survival than is being in the majority group. We did a systematic review and meta-analysis to assess whether psychological morbidity and health-related quality of life (HRQoL) were affected by minority status. ⋯ Prince of Wales Hospital, Sydney, Australia.
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The lancet oncology · Dec 2011
Multicenter StudyMocetinostat for relapsed classical Hodgkin's lymphoma: an open-label, single-arm, phase 2 trial.
The prognosis of patients with relapsed Hodgkin's lymphoma, especially those who relapse after stem-cell transplantation, is poor, and the development of new agents for this patient population is an unmet medical need. We tested the safety and efficacy of mocetinostat, an oral isotype-selective histone deacetylase inhibitor, in patients with relapsed classical Hodgkin's lymphoma. ⋯ MethylGene Inc, Montreal, Canada; Celgene Corporation, Summit, NJ, USA; Tufts Medical Center, Boston, MA, USA.
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The lancet oncology · Dec 2011
Randomized Controlled Trial Multicenter Study Comparative StudyFludarabine plus alemtuzumab versus fludarabine alone in patients with previously treated chronic lymphocytic leukaemia: a randomised phase 3 trial.
Chronic lymphocytic leukaemia (CLL) is an incurable and chronic disorder, with worsening prognosis for patients as their disease progresses. We compared the efficacy and safety of the combination of fludarabine and alemtuzumab with fludarabine monotherapy in previously treated patients with relapsed or refractory CLL. ⋯ Genzyme.