Journal of the Pediatric Infectious Diseases Society
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J Pediatric Infect Dis Soc · Dec 2020
Multicenter StudyMulticenter initial guidance on use of antivirals for children with COVID-19/SARS-CoV-2.
Although coronavirus disease 2019 (COVID-19) is mild in nearly all children, a small proportion of pediatric patients develop severe or critical illness. Guidance is therefore needed regarding use of agents with potential activity against severe acute respiratory syndrome coronavirus 2 in pediatrics. ⋯ Antiviral therapy for COVID-19 is not necessary for the great majority of pediatric patients. For those rare cases of severe or critical disease, this guidance offers an approach for decision-making regarding antivirals, informed by available data. As evidence continues to evolve rapidly, the need for updates to the guidance is anticipated.