Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
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Intracranial hypotension syndrome as a complication of diagnostic lumbar puncture is a rarely observed entity. Intracranial hypotension syndrome is characterized by postural headache, neck pain/stiffness, blurred vision, nausea, vomiting, clouding of consciousness, dizziness and vertigo. The majority of cases resolve spontaneously with conservative treatment. ⋯ A subdural hematoma was subsequently found, when the patient showed considerable worsening of clinical conditions with life-threatening symptoms. Surgical evacuation of the subdural hematoma was not sufficient to improve significantly the patient's conditions, while complete symptoms remission was achieved 12 hours after epidural blood patch. We stress the need for epidural blood patch in any case of post-diagnostic lumbar puncture postural headache which does not resolve with conservative therapy.
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Letter Clinical Trial
Baclofen is effective in intractable hiccups induced by brainstem lesions.
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Autosomal recessive ataxias are a heterogeneous group of rare neurodegenerative diseases characterized by early onset cerebellar ataxia associated with various neurologic, ophthalmologic and systemic signs. In comparison with autosomal dominant ataxias, the group of recessive ataxias is less extensively characterized. In fact, only a few conditions have been genetically characterized. ⋯ Some of these diseases exhibit a peculiar regional distribution. An updated review of the clinical, genetic, and pathogenic aspects of recessive ataxias is presented. Specific management problems with respect to diagnosis and genetic counseling are discussed.
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Case Reports
Extraskeletal Ewing's sarcoma presenting with neurological symptoms. Report of two cases.
Extraosseous Ewing's sarcoma (EES) is an uncommon condition that may develop in soft tissues at any location. Neurological symptoms leading to diagnosis have been reported exceptionally. ⋯ Radiological images showed a paraspinal mass in both cases and biopsy disclosed the histological features of Ewing's sarcoma. EES should be kept in mind in the differential diagnosis of paraspinal soft tissues tumours at any age.