Modern rheumatology
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Modern rheumatology · Jul 2017
An open-label, long-term, phase III extension trial of duloxetine in Japanese patients with fibromyalgia.
We aimed to evaluate the long-term safety and efficacy of duloxetine 60 mg in Japanese patients with fibromyalgia enrolled from a preceding randomized, placebo-controlled, phase III duloxetine trial. ⋯ Duloxetine was safe and effective in the long-term treatment of Japanese patients with fibromyalgia.
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Modern rheumatology · Jul 2017
Evaluation of paravertebral muscle atrophy and fatty degeneration in ankylosing spondylitis.
The purpose of this study was to assess morphological changes in the paravertebral muscles in patients with ankylosing spondylitis. ⋯ Chronic inflammation, cytokine-mediated fibrosis, immobilization, and postural changes in ankylosing spondylitis contribute to fatty degeneration and atrophy in the paravertebral muscles.