Cardiovascular diagnosis and therapy
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Cardiovasc Diagn Ther · Jun 2016
Therapeutic hypothermia impacts leukocyte kinetics after cardiac arrest.
Patients admitted to the hospital after primarily successful cardiopulmonary resuscitation (CPR) are at a very high risk for neurologic deficits and death. Targeted temperature management (TTM) for mild therapeutic hypothermia has been shown to improve survival compared to standard treatment. Acute cardiovascular events, such as myocardial infarction (MI), are a major cause for cardiac arrest (CA) in patients who undergo CPR. Recent findings have demonstrated the importance and impact of the leukocyte response following acute MI. ⋯ Our data underline the beneficial effects of TTM and demonstrate an impact of hypothermia on leukocyte counts after CA.