Archives of oral biology
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Archives of oral biology · Dec 2009
Involvement of medullary dorsal horn glial cell activation in mediation of masseter mechanical allodynia induced by experimental tooth movement.
To investigate the involvement of microglial and astrocytic activation in the medullary dorsal horn (MDH) during the mediation of masseter area allodynia induced by experimental tooth movement (ETM). ⋯ These results indicate that mechanical allodynia in the masseter area induced by ETM can be attenuated by minocycline. Activation of microglia, possibly together with subsequent activation of astrocytes, seems to contribute to masseter mechanical allodynia.