Acta Europaea fertilitatis
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Our work with a group involved in Assisted Conception (AC) has provided us with a perfect opportunity for making an assessment of the efficiency of the techniques used for the treatment of Male Antisperm Autoimmunization (MAA) and Female Antisperm Isoimmunization (FAI). The aim of this study is to present all the most important methods of AC used by our group for the treatment of immunological infertility, such as intrauterine insemination, intraperitoneal insemination, intrafallopian gamete transfer, in-vitro insemination and intrauterine embryo transfer, intrafallopian zygote transfer, intrafallopian embryo transfer, and gamete micromanipulation. In-vitro fecundation would appear to be particularly efficient in cases of FAI, while MAA would seem to benefit more from the use of gamete micromanipulation.
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Both the male and female partners of 28 couples with muco-semen incompatibility and of 8 couples with unexplained infertility were examined for the presence of genital infections by Chlamydia T. and/or Mycoplasma H. and/or Ureaplasma U. (CMU infections), and for topical and serum antisperm antibodies (AS-abs). The presence of other common genital infections, and for Candida A. and Trichomonas had previously been excluded in all the subjects; all the female partners presented normal hysterosalpingographs, regular ovulatory function and cervical score > or = 10. The main cause of the muco-semen incompatibility was dysspermia (35.7%), either associated or not with male CMU infections, followed by female CMU infections (21.4%), male CMU infections without dysspermia (3.6%), and the presence of AS-abs in the mucus (3.6%) and in the semen (3.6%); in 32.6% of the cases no plausible explanation was found for muco-semen incompatibility. ⋯ None of the patients with CMU infections showed AS-abs either in the semen and/or in the serum. AS-abs were found in the serum of 25% of the female patients with so-called "unexplained" infertility. CMU infections are important for the determination of muco-semen incompatibility, both with and without dyspermia.(ABSTRACT TRUNCATED AT 250 WORDS)
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Between June 1978, when the Law nr. 194 was introduced, and the end of 1979, about 250,000 legal abortions were carried out in Italy. Wide discrepancies exist among Italian Regions. ⋯ Minors and Women in the second trimester of pregnancy are still particularly prone to recourse to clandestine abortion. Conscientious objection is a major limiting factor in the implementation of the law.