Sheng wu gong cheng xue bao = Chinese journal of biotechnology
-
Sheng Wu Gong Cheng Xue Bao · Jun 2018
Review[Applications of simulated gastro-intestinal model in foodborne pathogens: tolerance and pathogenesis].
We evaluated the tolerance and pathogenesis of foodborne pathogens with a simulated gastro-intestinal tract model that simulates the chemical, physical and biological effects of human digestion process under laboratory conditions. This could be used to study the tolerance, pathogenesis, gut microbiota interaction and vaccine development of foodborne pathogens, so as to contribute to control and treatment of foodborne pathogens. ⋯ Also, the shortcomings of existing models are analyzed, and improvements of artificial gastro-intestinal tract model are prospected. In conclusion, this review could provide comprehensive data for promoting the progress of studying tolerance and pathogenesis of foodborne pathogens.