Current drug metabolism
The most recent articles from:
January 2018
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Current drug metabolism · Jan 2018
ReviewReplacing GHB with GBL in Recreational Settings: A New Trend in Chemsex.
Recently, Gamma-hydroxybutyrate (GHB) consumption in the recreational setting has been replaced by that of its prodrug Gamma-butyrolactone (GBL), cheaper and easier to obtain due to several legal industrial applications. ⋯ GBL currently represents a growing public health issue since the substance is relatively cheaper and easier to obtain than GHB. Improvement and implementation of laws and policies to place GBL under control are needed to limit its diffusion, the eventual health threat for users and its non -negligible abuse liability and dependence risk.