Klinische Neuroradiologie
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Klinische Neuroradiologie · Aug 2009
Case Reports[Cervical epidural abscess following lumbar epidural steroid injections].
A 49-year-old female with diabetes and chronic low back pain was treated with computed tomography-guided injections after years of unsuccessful pain management. Magnetic resonance imaging (MRI) demonstrated degenerative changes of the lumbar spine with disk herniation, facet joint degeneration, and instability of the presacral segment. Following epidural steroid injection, local infection and sepsis occurred and, finally, tetraparesis developed. ⋯ Legal proceedings were initiated against the radiologists. They were accused of causing damage to the patient. The plaint was defeated with special reference to the report and expertise of the neuroradiologic evidence.
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Klinische Neuroradiologie · Mar 2009
ReviewAcute and prophylactic endovascular treatment of internal carotid artery stenosis.
Stroke is the third most common cause of death in the USA. Up to 20% of all strokes are caused by internal carotid artery (ICA) stenosis. This article reviews the treatment of ICA stenosis, its indication, and its relevance for stroke prevention. The article also discusses the indication of ICA stenosis treatment in an acute stroke situation and offers pathophysiological commentary.
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Acute stroke imaging has developed from intraarterial angiography and native, unenhanced CT to highly elaborated tools with the access to a variety of pathophysiological variables ahead of therapy. Despite enduring unresolved problems, we can now obtain a comprehensive view on the individual patient's disease and act fast and specifically under consideration of chances and risks of different therapies. The stroke neuroradiologist is the decisive partner of engaged clinical disciplines and should own a leading role in future acute stroke trials. Weighing the different modalities against each other, there is an established advantage of acute stroke MRI over CT based on diffusion-weighted imaging and the possibility to obtain even more functional information on stroke pathophysiology.
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This article includes a review of major intravenous and endovascular stroke trials, treatment options, and future aspects of acute stroke treatment in hemispheric and vertebrobasilar stroke. Since the invention of local intraarterial thrombolysis by Hermann Zeumer in 1981, acute stroke diagnostics and treatment have undergone dramatic improvement. ⋯ The most promising approach in acute stroke treatment seems to be a combination of intravenous and endovascular revascularization procedure, combining early treatment initiation with direct clot manipulation and PTA/stenting in underlying stenosis with atherothrombotic occlusions. Further randomized studies comparing intravenous and endovascular treatment, mainly in the anterior circulation, have to be expected and need wide support of the neurologic and neuroradiologic stroke community.