Heart, lung & circulation
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Heart, lung & circulation · May 2013
Randomized Controlled TrialDoes glutamine promote benefits for patients with diabetes mellitus scheduled for cardiac surgery?
We hypothesised, that perioperative use of N(2)-L-alanyl-L-glutamine confers cardioprotection and improves insulin resistance in diabetic patients with coronary artery disease operated under cardiopulmonary bypass. ⋯ Our results have failed to confirm the cardioprotective properties and modulatory effect on perioperative insulin resistance that are thought to be attributable to parenteral glutamine administration in dose 0.4 g/kg/day among cardiac patients with DM operated on under CPB.