Intensive care medicine experimental
-
Intensive Care Med Exp · Jul 2020
Water content of the endothelial glycocalyx layer estimated by volume kinetic analysis.
The water volume of the endothelial glycocalyx layer has been estimated at 0.7 to 1.7 L using tracer methods of unclear value. The present study attempts to measure this fluid volume by analyzing the kinetics of a crystalloid fluid load. ⋯ A crystalloid fluid load expands a 0.4-0.5 L larger central fluid space than the circulating plasma volume. The excess volume is probably located in the glycocalyx layer.