Asian journal of transfusion science
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Asian J Transfus Sci · Jan 2012
Recombinant-activated factor VII in patients with uncontrolled bleeding: A retrospective observational analysis.
Factor VIIa (recombinant) has an off-label use to control life-threatening bleeding that is refractory to other measures and was shown to decrease transfusion requirements. ⋯ The use of rFVIIa appears to be safe and effective in promoting hemostasis, as evident from reducing transfusion requirements and improving the coagulation variables.