United European gastroenterology journal
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United European Gastroenterol J · Dec 2019
Meta AnalysisEfficacy and safety of biologic agents and tofacitinib in moderate-to-severe ulcerative colitis: A systematic overview of meta-analyses.
Ulcerative colitis (UC) is an inflammatory disease of the colon and rectum. Treatment options include biologics and tofacitinib. ⋯ Biologics and tofacitinib are efficacious and safe for treating UC. These findings can support clinical decision-making.
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United European Gastroenterol J · Dec 2019
Multicenter StudyMean muscle attenuation correlates with severe acute pancreatitis unlike visceral adipose tissue and subcutaneous adipose tissue.
Acute pancreatitis (AP) is a frequent disorder with considerable morbidity and mortality. Obesity has previously been reported to influence disease severity. ⋯ Our results demonstrate that a low muscle attenuation level is associated with an increased risk of severe AP. Future prospective studies will help identify the underlying mechanisms and characterise the influence of body composition parameters on AP.