Swiss medical weekly
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Swiss medical weekly · May 1980
Case Reports[Pancreatic cancer associated with pancreatitis and pseudocysts].
A discussion is presented of the diagnostic problems encountered in 27 of 153 consecutive cases of pancreatic cancer, all of which were initially misinterpreted as acute (relapsing) or chronic pancreatitis or pancreatic pseudocysts.
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The effect of lysolecithin on gastric mucosa in rats has been investigated using a new operative model. Ten rats underwent sham-laparotomy. In 4 other groups, each of 10 animals, the rats underwent pyloro-jejunostomy and Roux-en-Y anastomosis. 9 of 10 rats operated upon in this way, and given a solution of lysolecithin to drink before administration of restraint stress, produced stress ulcers. ⋯ Lysolecithin not combined with stress had no noteworthy deleterious effect on gastric mucosa either in sham-operated rats or in those with our operation model. Thus, lysolecithin combined with stress in our model performed an important function in the pathogenesis of stress lesions. Lysolecithin is produced in considerable quantities during fat metabolism in the intestine, and may be regurgitated together with duodenal contents into the stomach.