Swiss medical weekly
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Swiss medical weekly · Apr 1982
[Acral-lentiginous melanoma: the newest subgroup of malignant melanomas of the skin].
A new subgroup of malignant melanoma, acral-lentiginous melanoma (ALM), is presented, which the authors have diagnosed in 8% of their melanoma patients. In a retrospective study the clinical and pathological findings in 44 patients with ALM are reviewed. A relationship was found between age, tumor diameter and thickness, pigmentation, ulceration, vasoinvasion and mitoses. The author's patients had a 5-year survival rate of 58%.
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Swiss medical weekly · Apr 1982
[Prevention of cytostatic-related hair loss by hypothermia of a hairy scalp using a cooling cap].
82 patients treated with adriamycin alone or in combination with other cytostatic agents underwent scalp hypothermia by application of a gel cap. The cap ws applied 10 minutes before the injection of the drugs and maintained until 30 minutes after the administration of the chemotherapy. ⋯ No statistically significant difference was found between patients receiving higher or lower doses of adriamycin or between patients wtih or without liver dysfunction. The tolerance of the gel cap was excellent; only one patient did not tolerate the cap because of anxiety during application.