Swiss medical weekly
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Swiss medical weekly · Jan 1998
[Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA)].
Long-term health effects of moderate ambient air pollution are rarely investigated. In Switzerland, no large-scale study has addressed this issue so far. Important results of the Swiss Study on Air Pollution and Lung Disease in Adults (SAPALDIA) are presented. ⋯ Health effects of moderate air pollution were confirmed in Switzerland. Although for the individual the relative risks are small, the public health impact may be considerable. An ongoing follow-up will investigate the mortality profile of the SAPALDIA cohort.
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Swiss medical weekly · Jan 1998
Review[Positron-emission tomography in the diagnosis of abdominal tumors].
PET is recognized as a powerful imaging research tool. Its clinical application has been increasing significantly in recent years. Based on pathophysiological and biochemical principles, functional PET imaging makes it possible to assess parameters of tumor biology not easily accessible to conventional imaging, such as metabolic activity, proliferation, adrenergic transmitter uptake or accumulation of cytostatics in individual tumor manifestations. ⋯ Several appropriately labeled adrenergic transmitters are currently being developed for specific imaging of neuroendocrine tumors. Radiolabeled cytostatics such as F-18 5-FU will shortly be available for clinical use as probes for primary or secondary cytostatic resistance. Encouraging clinical results and attractive new imaging concepts promise increasing use and importance for PET for imaging of abdominal malignancies.