Swiss medical weekly
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Swiss medical weekly · Aug 2001
Randomized Controlled Trial Clinical TrialWearing a noseclip improves nebulised aerosol delivery.
The efficiency of nebulised aerosol delivery is limited due to drug retained within the nebuliser, and due to a poor ratio between inspiratory drug delivery and expiratory drug loss. Several technical approaches have improved the ratio between inspiratory aerosol delivery and expiratory aerosol loss. In our pilot study we aimed to investigate if wearing a noseclip during inhalation therapy improves the inspiratory versus expiratory ratio and hence, improves nebulised aerosol delivery. ⋯ We have shown that aerosol delivery is increased due to an improved inspiratory versus expiratory ratio when wearing a noseclip.