Journal of the renin-angiotensin-aldosterone system : JRAAS
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J Renin Angiotensin Aldosterone Syst · Jun 2014
Review Meta AnalysisThe -344C/T polymorphism in the CYP11B2 gene is associated with essential hypertension in the Chinese.
It has been suggested that the -344C/T polymorphism in the CYP11B2 gene is involved in the development of hypertension. However, the results have been inconsistent. In this study, a meta-analysis was performed to clarify the association of -344C/T polymorphism in the CYP11B2 gene with hypertension risk in the Chinese population. ⋯ Our study suggested that the -344T/C polymorphism in the CYP11B2 gene was significantly associated with hypertension in the Chinese population, especially in the Han Chinese.