Diabetologia
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Multicenter Study
Association between age at menarche and risk of diabetes in adults: results from the EPIC-Norfolk cohort study.
Earlier age at menarche is associated with increased BMI and obesity risk from early childhood through to adulthood. We hypothesised that earlier age at menarche would also predict subsequent diabetes risk. ⋯ Earlier age at menarche increases the risk of diabetes in women and this association appears to be mediated by increased adiposity. History of earlier menarche may help to identify women with increased subsequent risk of diabetes.