Diabetologia
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Previous studies have suggested an increased risk of bladder cancer with pioglitazone exposure. We aimed to investigate the association between pioglitazone exposure and bladder cancer in France. ⋯ In this cohort of diabetic patients from France, pioglitazone exposure was significantly associated with increased risk of bladder cancer.
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Randomized Controlled Trial Multicenter Study
Physical activity reduces the risk of incident type 2 diabetes in general and in abdominally lean and obese men and women: the EPIC-InterAct Study.
We examined the independent and combined associations of physical activity and obesity with incident type 2 diabetes in men and women. ⋯ Physical activity is associated with a reduction in the risk of developing type 2 diabetes across BMI categories in men and women, as well as in abdominally lean and obese men and women.
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The study aimed to explore the variation in recorded incidence of lower limb amputation in England. ⋯ Variation in amputation incidence occurs across England. Because of the similarity in amputation variation between people with and without diabetes the variation may reflect generic differences in local healthcare delivery, although racial factors may also contribute.