Radiologic clinics of North America
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The diagnosis of common and opportunistic infections in patients with HIV begins with clinical suspicion and involves relatively standard methodology. Musculoskeletal infection is sometimes the first manifestation of an HIV infection. In patients with HIV, the infections tend to be more advanced at presentation, occur in unusual sites, are caused by a wider spectrum of pathogens, and tend to show an inadequate or delayed response to therapy. The index of suspicion for musculoskeletal infections should be high when reviewing imaging studies of patients with HIV.
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The presence of infectious spondylodiskitis and its complications may present protean clinical and imaging findings. The frequent use of multi-imaging modalities has led to a greater sensitivity and specificity in the diagnosis of this ubiquitous disease.