ANZ journal of surgery
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ANZ journal of surgery · Mar 2013
Five-year results of surgical colorectal cancer treatment in rural Australia.
The incidence of colorectal cancer in Australia is among the highest worldwide. We investigate whether similar treatment results for colorectal cancer can be achieved in rural surgery as reported from metropolitan centres. ⋯ Assessment of overall and cancer-specific survival of all patients undergoing surgery for colorectal cancer over a 5-year time period in a rural South Australian centre shows that good long-term results can be achieved with low perioperative mortality. These findings compare well with the results of other groups.
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Bisphosphonates decrease the risk of typical low trauma fractures, and are commonly prescribed for this indication. The link between atypical fractures and bisphosphonate use is well established; however, who is susceptible to atypical fracture remains unclear. A number of large population-based studies have disregarded the atypical fracture risk as they have found the absolute risk to be low. ⋯ The burden of bisphosphonate-associated atypical fractures is significant. The aetiology of these fractures is unclear, and to date, no studies have demonstrated the significance of the injury for the patient. Prescription of bisphosphonate therapy for osteoporosis should be accompanied by ongoing surveillance and warning of the possibility of atypical and minimal trauma fractures.