Journal of rehabilitation medicine : official journal of the UEMS European Board of Physical and Rehabilitation Medicine
-
Randomized Controlled Trial
Effects of botulinum toxin A in ambulant adults with spastic cerebral palsy: a randomized double-blind placebo controlled-trial.
This study aimed to assess short-term effects of botulinum toxin A in ambulant adults with spastic cerebral palsy. ⋯ Botulinum toxin A injections alone gave no benefit over placebo in lower limb sagittal kinematics and Short Form 36 in ambulatory adults with cerebral palsy. However, self-reported rating of muscle-stiffness/spasticity and global effects indicated positive effects of botulinum toxin A. Further studies with specific post-injection rehabilitation and longer study period are warranted.