Archives of environmental health
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Groups of male Swiss-Webster mice breathed emissions of several brands of crib mattresses for two 1-hr periods. The authors used a computerized version of ASTM-E-981 test method to monitor respiratory frequency, pattern, and airflow velocity and to diagnose abnormalities when statistically significant changes appeared. The emissions of four mattresses caused various combinations of upper-airways irritation (i.e., sensory irritation), lower-airways irritation (pulmonary irritation), and decreases in mid-expiratory airflow velocity. ⋯ Organic cotton padding caused very different effects, evidenced by increases in both respiratory rate and tidal volume. The authors used gas chromatography/mass spectrometry to identify respiratory irritants (e.g., styrene, isopropylbenzene, limonene) in the emissions of one of the polyurethane foam mattresses. Some mattresses emitted mixtures of volatile chemicals that had the potential to cause respiratory-tract irritation and decrease airflow velocity in mice.