Giornale di batteriologia, virologia, ed immunologia ed annali dell'Ospedale Maria Vittoria di Torino
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G Batteriol Virol Immunol · Jan 1990
[Gangrenous and perforating appendicitis in a provincial hospital: a 48-month retrospective study. Clinical and microbiological aspects, course and postoperative morbidity].
The appendectomy for gangrenous or perforated appendicitis is made more serious by a very high frequency of infection. The antibiotic prophylaxis should be able to reduce the frequency of such complications. We have considered retrospectively the patients who underwent appendectomy for gangrenous and perforated appendicitis in the period from June 1st, 1986 to May 31st 1990 in the Ivrea-Castellamonte hospital (Province of Turin), focusing our attention on certain microbiological and clinical variables in relation to the post-operative course. ⋯ The per-operative cultures of pus coming from the peritoneum cavity were positive in 83.7% of the cases (53.5% mixed aerobe-anaerobe cultures). The microorganism most frequently isolated were: Escherichia coli (27.7%), Bacteroides fragilis (7.9%), other Bacteroides spp. (20.8%), among the positive gram aerobes the Streptococcus milleri (6.9%) prevails; the most common association is the between Bacteroides spp. and Enterobacteria (19 cases); in a good 17 cases the enterobacteriaceae is represented by the Escherichia coli; the Bacteroides, E. coli and Streptococcus association is, however, observed in 10 cases. Our study confirms the usefulness of the peri-operative antibiotic prophylaxis in the cases of a gangrenous or perforated appendicitis.