Internal medicine journal
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Internal medicine journal · Dec 2016
ReviewRecent treatment advances in Hodgkin lymphoma: a concise review.
The majority of patients with Hodgkin lymphoma enjoy durable remissions following front-line treatment. This typically involves combination chemotherapy with or without radiotherapy. A significant minority of patients experience relapsed/refractory disease, of whom only approximately half can be 'salvaged' with conventional second-line treatments. ⋯ Individualising and adapting a patient's treatment course, whether augmenting or rationalising therapy, based on an interim positron emission tomography/computed tomography response is an important strategy currently under exploration to minimise toxicity while maximising response. Further work is needed to explore clinical and biological factors associated with improved outcomes. Knowledge of these factors combined with the movement of novel therapies into the front-line setting will enable individualised therapy to enhance clinical responses and minimise toxicities.
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Internal medicine journal · Dec 2016
Patient characteristics, interventions and outcomes of 1151 rapid response team activations in a tertiary hospital: a prospective study.
The characteristics of mature contemporary rapid response systems are unclear. ⋯ Relatively few RRT activations are associated with acute resuscitation plans, and most interventions during RRT responses are low level. The high rate of post-RRT deaths and transfers to higher-level care units calls for the prospective identification of such patients in targeting appropriate care.
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Internal medicine journal · Dec 2016
Letter Case ReportsKimura disease in a Maori man with nephrotic syndrome.