Deutsche zahnärztliche Zeitschrift
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Randomized Controlled Trial Clinical Trial
[General complications in dental local anesthesia].
In a prospective, randomised double blind study we recorded the rate of complications in dental anesthesia in more than 1500 patients using 4 commonly known anesthetic solutions. 228 of our patients (18.3%) noted headaches postoperatively. Furtheron we found syncopes, failures of anesthesia and nausea. Double vision was noticed once intraoperatively (Articain) and postoperatively (Lidocain). We found a high standard of security in dental local anaesthesia.
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Comparative Study
[Perineural application of glycerol and phenol-glycerol. Histomorphologic-morphometric study].
In a long-term study the effect of glycerol and phenol-glycerol on rats mandibular nerve was analysed. The substances were applicated perineurally. Nerves treated with glycerol did not show any severe pathological changes. ⋯ On the contrary, nerves treated with phenol-glycerol showed the familiar picture of degeneration and regeneration. According to our results it can be stated that the perineural application of glycerol has no toxic and destructive effect on the nerve. Therefore, the perineural glycerol blocking will not cause severe side-effects and the method can be recommended in the therapy of chronic facial pain.
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Neurosensory disturbances of the third branch of the trigeminal nerve occur in rare cases without any operative treatment near the nerve involved. The most frequently affected nerve branches are the inferior alveolar nerve and the lingual nerve. ⋯ After intraneural injection of Articain (4%)-solution in the ischiadic nerve of Wistar rats and the lingual nerve of cats no toxic lesions were observed. It can be assumed that neurosensory disturbances caused by intraneural local-anaesthetic injection are the result of intraneural haematomas with consecutive fibrosis.