Best practice & research. Clinical gastroenterology
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Best Pract Res Clin Gastroenterol · Feb 2018
ReviewAcute severe ulcerative colitis: State of the art treatment.
Acute severe ulcerative colitis (ASUC) is a potentially life-threatening condition. In the present review, we give a broad overview of the state of the art in the management of this condition. A systematic bibliographic search was performed in PubMed. ⋯ More recently, infliximab has become the most widely used salvage therapy. Third-line salvage therapy with either cyclosporin or infliximab is efficacious in some patients but carries a significant risk of complications. Colectomy is appropriate in case of complications or medical rescue therapy failure.