Best practice & research. Clinical rheumatology
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Best Pract Res Clin Rheumatol · Dec 2005
ReviewHow many people develop fractures with what outcome?
Osteoporosis is an important clinical and public health problem because of its association with fractures. Osteoporotic fractures result in significant morbidity, mortality and health and social care costs. ⋯ Over and above this demographic trend there is evidence that the age-specific rates of fractures have increased during the last century. This chapter reviews the epidemiology of osteoporotic fractures, including their occurrence, descriptive epidemiology and impact.
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Best Pract Res Clin Rheumatol · Dec 2005
ReviewIn whom and how to prevent glucocorticoid-induced osteoporosis.
Glucocorticoid use is widespread in medicine. While it is often life-saving, side-effects are well known. ⋯ Today we have therapies with proven efficacy for the prevention of vertebral fractures and bone loss. Consequently recognition of glucocorticoid-induced osteoporosis is extremely important given the availability of effective therapy.