Clinical biochemistry
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Clinical biochemistry · Jul 2000
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialAnalytical and diagnostic performance of troponin assays in patients suspicious for acute coronary syndromes.
The controversy whether there is a clinically significant difference between troponin T (cTnT) and troponin I (cTnI) in regard to predictive value and cardiac specificity is still ongoing. ⋯ By using the defined threshold values and the employed test systems, single testing for cTnI and cTnT within 12 h after symptom onset was appropriate for risk stratification. Despite the lower cardiac specificity for cTnT, it appears to have a stronger association with the patients' outcome, whereas, as previously shown, the ability to identify patients who benefit from treatment with a GP IIb/IIIa receptor antagonist is similar.