Clinical biochemistry
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Clinical biochemistry · Mar 2008
ReviewDiagnostic accuracy of BNP and NT-proBNP in patients presenting to acute care settings with dyspnea: a systematic review.
We sought to compare the diagnostic performance of B-type natriuretic peptide (BNP) and N-terminal proBNP measurements in patients presenting to acute care settings with dyspnea, a common presenting symptom of heart failure. ⋯ BNP and NT-proBNP have very similar diagnostic performance characteristics and can be used to rule out heart failure as a cause of dyspnea in the acute clinical setting. However, there is no easily identifiable optimum cut point value for each peptide.