Expert review of anticancer therapy
-
Expert Rev Anticancer Ther · Aug 2009
ReviewOsteonecrosis of the jaw and bisphosphonate use in breast cancer patients.
It is renowned that breast cancer patients suffer from a number of cancer-related skeletal events, while drugs recently added to the practitioners' quiver, such as aromatase inhibitors, intensify the need to preserve bone mass in this group of patients. Bisphosphonates are potent inhibitors of both normal and pathologic bone resorption. ⋯ The purpose of this review is to critically reflect the incidence, etiopathogenesis, prevention and treatment of osteonecrosis of the jaw. Succinct suggestions are provided to ensure clinicians prevent and detect the complications early.