Expert review of anticancer therapy
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Expert Rev Anticancer Ther · Jul 2014
ReviewThe multidisciplinary management of giant cell tumor of bone.
Giant cell tumor of bone is a locally aggressive lesion with a predilection for local recurrence, and in a small proportion of patients, metastatic disease can develop. Surgery is the mainstay of management for extremity-based lesions. ⋯ Serial arterial embolization can be effective in some cases. Recent evidence has demonstrated denosumab to be a promising agent in the treatment of unresectable or metastatic disease.