The international journal of lower extremity wounds
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Int J Low Extrem Wounds · Mar 2021
Comparison of the Effect of Local and Systemic Injection of Resveratrol on Cutaneous Wound Healing in Rats.
Purpose. To compare the effect of local and systemic injection of resveratrol (RSV) on open cutaneous wound healing. Materials and Methods. ⋯ Systemic and local RSV administrations significantly enhanced wound healing and increased the tensile strength of the skin in rats. Conclusion. Local subcutaneous application of RSV may have a better therapeutic effect than the systemic application of RSV in terms of neovascularization to promote wound healing.