Expert review of neurotherapeutics
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Hemicrania continua (HC) is a primary headache disorder that is characterized by a continuous unilateral headache of moderate severity, exacerbations of severe pain, and complete responsiveness to indomethacin. Misdiagnosis of HC is probably common in general neurology settings and other clinical specialties. This paper is an attempt to bridge the gap between the correct and misdiagnosis of this disorder. ⋯ HC can be of continuous or remitting form. Variants such as HC with aura have been described and secondary cases may occur. Indomethacin is the best treatment, although HC could respond to other NSAIDs, such as the selective COX-2 inhibitors.
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Expert Rev Neurother · Sep 2009
ReviewAdverse effects of medications commonly used in the treatment of migraine.
The classes of medications for migraine treatment are numerous and include ergots, triptans, NSAIDs, antidepressants, anti-epilepsy drugs, antihypertensives and natural supplements. Physicians need to be aware not only of medication efficacy but also of tolerability and safety. ⋯ However, these same coexistent conditions can be worsened by migraine medication or be contraindicated and multiple medications prescribed for several conditions can result in drug-drug interactions. This article reviews adverse events associated with migraine and medications, and their implications in clinical treatment.