Expert review of neurotherapeutics
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Expert Rev Neurother · Sep 2011
ReviewAntiganglioside antibodies in Guillain-Barré syndrome and its related conditions.
Guillain-Barré syndrome (GBS) is typically classified into two major subtypes: acute inflammatory demyelinating neuropathy and acute motor axonal neuropathy. Its most recognizable variant is Fisher syndrome. ⋯ In this article, we discuss the different clinical presentations in GBS and the role of antiganglioside antibodies in their underlying pathogenesis. We also discuss the impact that antiganglioside antibodies have had in the development of experimental models and treatment modalities in GBS.