The Lancet infectious diseases
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Review Meta Analysis
Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis.
Many meta-analyses have shown reductions in infection rates and mortality associated with the use of selective digestive decontamination (SDD) or selective oropharyngeal decontamination (SOD) in intensive care units (ICUs). These interventions have not been widely implemented because of concerns that their use could lead to the development of antimicrobial resistance in pathogens. We aimed to assess the effect of SDD and SOD on antimicrobial resistance rates in patients in ICUs. ⋯ None.