The spine journal : official journal of the North American Spine Society
-
Review Case Reports
Controversies in the treatment of cervical spine dislocations.
Cervical spine dislocations represent an area of great controversy among spine surgeons. ⋯ Guidelines for the management of cervical spine dislocations are presented based on evidence-based medicine.
-
Randomized Controlled Trial Multicenter Study
Prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of lumbar total disc replacement with the CHARITE artificial disc versus lumbar fusion: five-year follow-up.
The CHARITE artificial disc, a lumbar spinal arthroplasty device, was approved by the United States Food and Drug Administration in 2004 based on two-year safety and effectiveness data from a multicenter, prospective, randomized investigational device exemption (IDE) study. No long-term, randomized, prospective study on the CHARITE disc or any other artificial disc has been published to date. ⋯ The results of this five-year, prospective, randomized multicenter study are consistent with the two-year reports of noninferiority of CHARITE artificial disc vs. ALIF with BAK and iliac crest autograft. No statistical differences were found in clinical outcomes between groups. In addition, CHARITE patients reached a statistically greater rate of part- and full-time employment and a statistically lower rate of long-term disability, compared with BAK patients. Radiographically, the ROMs at index- and adjacent levels were not statistically different from those observed at two-years postsurgery.
-
A recent study involving interbody fusion patients found that preoperative work status was significantly related to clinical outcome. In another study comparing the best and worst outcomes of total disc replacement, among a battery of variables analyzed, the only one that differentiated the best and worst outcome groups was the length of time off work before total disc replacement. ⋯ The results of this study found that patients off work for a longer duration before surgery improved significantly postoperatively, but had less favorable clinical outcomes than patients off work for a lesser duration. This study suggests a window of approximately 13 weeks off work before surgery after which clinical improvement is reduced. Implications of this finding may be that once a patient becomes unable to work for an extended period, more rigorous psychological screening may be in order as well as perhaps engaging in more rigorous rehabilitation after surgery. Further investigation is needed to determine if the 13 weeks identified in this study is applicable to other populations.
-
Primary tumors of the sacrum are extremely rare lesions. Their management is governed by an interplay of complex factors. Appropriate decision making is crucial to obtain the best possible outcome in terms of maximizing disease control while attempting to minimize neurological dysfunction. ⋯ Wide resection with adequate margins gives the best chance of local control and should be the surgery of choice for all malignant primary sacral tumors and in benign lesions involving lower segments when preservation of both S3 roots is possible. Intralesional curettage has a higher risk of local recurrence without providing the certainty of retaining neurological function. To retain bladder and bowel control and minimize neurological dysfunction, it may be worthwhile managing benign sacral tumors that extend above S3 with serial embolization. The administration of parenteral bisphosphonates may prove beneficial in cases of giant cell tumor managed with serial embolization.