Articles: disease.
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Age-related macular degeneration (AMD), a condition of multifactorial origin, is a major cause of irreversible vision loss in industrialized countries. The dry late stage of the disease, known as geographic atrophy (GA), is characterized by progressive loss of photoreceptor cells and retinal pigment epithelial cells in the central retina. An estimated 300 000 to 550 000 people in Germany suffer from GA. ⋯ In Europe at present, there is no approved treatment for GA due to AMD. There is thus a continuing need for preventive and rehabilitative measures such as smoking cessation, a balanced diet, and magnifying visual aids for patients in the advanced stages of the disease.
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Achalasia is a rare disease of gastrointestinal motility characterized by impaired esophageal peristalsis and reduced esophageal sphincter relaxation. However, data on its epidemiology and outcomes in Taiwan are limited. This study aimed to assess the incidence, characteristics, and clinical management of achalasia in Taiwan. ⋯ This is the first population-based epidemiological study on achalasia in Taiwan, revealing the incidence of achalasia before the era of high-resolution manometry. Clinicians should be vigilant about the development of esophageal cancer and mortality during long-term follow-ups. There is also room to enhance the utilization of various diagnostic tools for achalasia.
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In the United States, older adults have elevated prevalence of latent tuberculosis infection (LTBI) and incidence of tuberculosis (TB). ⋯ Centers for Disease Control and Prevention.
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Mayo Clinic proceedings · Feb 2025
Comparison of Muscle Strength and Cardiorespiratory Fitness in Relation to Cardiovascular and All-Cause Mortality: The Copenhagen City Heart Study.
To compare the association between muscle strength (MS), cardiorespiratory fitness (CRF), and all-cause and cardiovascular disease (CVD) mortality. ⋯ Both CRF and MS are inversely associated with CVD mortality and all-cause mortality, but of the 2, CRF confers stronger protection.