Articles: low-back-pain.
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Multicenter Study Comparative Study Clinical Trial
Long-term tolerability of tramadol LP, a new once-daily formulation, in patients with osteoarthritis or low back pain.
Tramadol hydrochloride is a centrally acting analgesic, which possesses opioid agonist properties and activates monoaminergic spinal inhibition of pain. An oral, once a day, sustained release formulation of tramadol is thought to be advantageous compared with immediate release preparations as it prevents plasma peaks associated with increased side-effects of the drug. It may also improve compliance. The purpose of the study was to assess the long-term safety of a new sustained-release formulation of tramadol (tramadol LP) in patients with knee or hip osteoarthritis and in patients with refractory low back pain. ⋯ Long-term treatment with tramadol LP once daily is generally safe in patients with osteoarthritis or refractory low back pain.
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Qual Saf Health Care · Apr 2005
Randomized Controlled Trial Clinical TrialEffect on the process of care of an active strategy to implement clinical guidelines on physiotherapy for low back pain: a cluster randomised controlled trial.
To evaluate the effect on the process of care of an active strategy to implement clinical guidelines on physiotherapy for low back pain. ⋯ The active strategy moderately improved adherence to the guidelines. Active strategies are recommended to implement the clinical guidelines on physiotherapy for low back pain.
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Randomized Controlled Trial
A randomized clinical trial comparing two physiotherapy interventions for chronic low back pain.
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Lumbar provocation discography is an invasive diagnostic procedure to identify pain originating from within the lumbar discs. Specific morphological changes within the disc, classified as radial fissures, can be imaged following the injection of radiopaque contrast into the nucleus pulposus. The reproduction of concordant low back and/or referred somatic pain to the lower extremity under controlled conditions and the demonstration of annular radial tears are part of a spectrum of internal disc disruption that is separate from disc degeneration. A review of the validity and technique of lumbar discography as well as recently described causes of false positive responses are presented.
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Cross-sectional cohort study of a general population. ⋯ In children, degenerative disc findings are relatively common, and some are associated with LBP. There appears to be a gender difference. Disc protrusions, endplate changes, and anterolisthesis in the lumbar spine were strongly associated with seeking care for LBP.