Articles: nerve-block.
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Acta Anaesthesiol Scand · Mar 2004
Tetrodotoxin-induced conduction blockade is prolonged by hyaluronic acid with and without bupivacaine.
In isolated nerves, tetrodotoxin (TTX) blocks nerve conduction longer than bupivacaine. In vivo, however, both substances block nerve conduction to an equal duration, presumably because the hydrophilic TTX binds only weakly to the perineural tissue. High molecular weight hyaluronic acid (HA) prolongs the action of local anaesthetics several-fold. We tested whether admixture of HA enhances the binding of TTX to the perineural tissue and thus induces an ultra-long conduction block after a single application. ⋯ Both HA and HA/bupivacaine prolong the TTX-induced conduction blockade of the aortic nerve of rabbits in vivo. No signs of neurotoxicity were observed.
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Rev Esp Anestesiol Reanim · Feb 2004
Randomized Controlled Trial Comparative Study Clinical Trial[Sciatic nerve block with 1% mepivacaine for foot surgery: posterior versus lateral approach to the popliteal fossa].
To compare the efficacy and feasibility of the sciatic nerve block performed using either a posterior or a lateral approach to the popliteal fossa, taking into consideration patient comfort during puncture and postoperative analgesia. ⋯ The lateral approach to the block of the sciatic nerve in the popliteal fossa provides analgesia comparable to that obtained with the posterior approach, with a faster onset and longer postoperative duration.
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Major knee surgery can result in severe postoperative pain, especially in older people. When it is inadequately controlled, such pain can have a serious impact on the patient's physical state and their quality of life. This paper looks at the use in one hospital of femoral nerve block techniques to complement other pain-management methods following a total knee replacement operation.